Prostate Cancer Awareness Week
(pcaw.org) has compiled newsbytes on the prostate. Prostate Cancer
Awareness Month is September, and Prostate Cancer Awareness Week, the
period set aside for free or low-cost screenings, runs September
21-27, 2015. Information about the Prostate is added weekly. Also see
Archives 2 and 3.
Fewer Men Estimated to Die From Prostate
Recently released figures have indicated an estimated 26,120 men will die of prostate cancer in 2016, a 5 percent drop from the 2015 estimate. Based on these facts, a man will lose his prostate cancer battle every 20 minutes. In 2016, an estimated 180,890 men will be diagnosed with prostate cancer, an 18 percent decline from 2015 estimate
Advances in the treatment of prostate cancer have lead to a steady decline in deaths from the disease, but despite this good news, detection rates have fallen significantly in recent years. This is due to recommendations against PSA testing, causing more patients to be diagnosed in late stage disease and limiting their options for treatment.
Were concerned that lack of early detection will lead to
increases in deaths in the coming years and urge continued focus on
advancing diagnostic tools and technology focused on finding prostate
cancer early and determining aggressive from indolent disease.
Alternative Works Well, Spares Libido
Herbs Take a Whack at Prostate Cancer: Men
with fewest options seem to benefit most
Mayors Launch Coalition for
Prostate Cancer Awareness and Education
The Coalition was started thanks to the efforts of Denver Mayor
Wellington E. Webb. For more information, contact Richard C. Johnson,
Director of USCM Health Programs, 1620 Eye Street, NW, 3rd floor,
Washington, DC 20006 or 202.861.6753 or firstname.lastname@example.org
Prostate Cancer Climb - January,
Nine climbers and 12 trekkers will scale the mountain. All of them have been personally touched by prostate cancer. A few are prostate cancer survivors. Many have close friends or relatives in treatment for the disease. Several have lost loved ones to prostate cancer. All of them are "amateur" climbers - and are spending this year getting ready for this physically taxing challenge. The climb will take almost three weeks, and will be professionally led by SUMMITS Adventure Travel, a premier leader in the climbing industry.
The Prostate Cancer Climb is the inspiration of Dr. Terry Weyman, who lost his father to prostate cancer 10 years ago. The project is primarily a volunteer effort, and is affiliated with the Prostate Cancer Research Institute in order to provide the structure, accountability and recommendations on allocation of funding necessary for success.
Each climber will raise money to cover their individual costs for the climb, approximately $5,000 each. They will also solicit pledges for the "Prostate Cancer Climb" fund. Corporate, community and individual pledges are also being solicited to help reach our goal of raising $1,000,000 to help fight prostate cancer.
This is a low-overhead project, with the primary goal being to
raise $1 million to benefit prostate cancer research and public
education. The overall budget of the Prostate Cancer Climb is $1.3
million. It will take approximately $300,000 to produce the climb
(inclusive of climbers' costs) and the remaining $1 million is the
amount that will be donated to research and education about prostate
NFL Support Breast Cancer Research
Grosse Pointe is Gross
Male Character: "The normal prostate is the size of an apple seed."
Male actor: "However, left unchecked, cancer can cause it to grow to the size of a peach pit."
This material offensive and insulting to men in general and prostate cancer sufferers in particular? The most galling thing about this is that the show thinks they are being edgy and offbeat by offering this kind of humor. Can you imagine the reaction if they had made similar jokes about breast cancer or AIDS? There would be no need for this email because the show would be off the air by now. Hal McCown
If you want to express your displeasure, www.wb.com/pages/help/help_feedback.jsp
Prostate Cancer - What the choices are and
how they can affect your life
Urine Test Might Detect Prostate
Men With Vasectomies At Greater Risk For Prostate Cancer?
Dr. Dean: It's funny that you're doing the research and he's not.
Ellen: Well, he asked me to.
Dr. Dean: Ah-ha, chicken. I can definitively say to you that vasectomies do not cause prostate cancer. He should have no fear whatsoever about that. But at one point there was research that suggested a connection.
A couple of studies did find that men with vasectomies had more prostate cancer. Of course, the National Cancer Institute was very interested in these studies, but once news goes into a database on the Internet, it can stay there forever.
Our Web site is huge. The last time I checked we had 40,000 pages, because we want to share information with you. However, keeping material updated can be a challenge.
With further searching, I think you will find that subsequent studies indicate that "detection bias" skewed the earlier reports. Here is how detection bias works.
A man getting a vasectomy will see a urologist. As part of the pre-vasectomy physical, the urologist is going to put his finger where the sun don't shine and examine the patient's prostate. Therefore, prostate cancer is going to be detected more often in men getting vasectomies than in other men. Thus, it appears that men getting vasectomies have more prostate cancer.
There is some research, that is still inconclusive, indicating that primates (monkeys) with vasectomies, may have higher cholesterol levels and greater risk factors for heart disease.
We have NOT found vasectomies to increase heart attacks in humans. Nevertheless, because primates are so close to us, the question, however minimal, lingers.
The question wouldn't stop me from having a vasectomy if I needed one. When I did need one, I didn't do it; and that's why I've got so many kids. And, of course, I'm glad I did.
I tell you in all honesty, Ellen, that when a couple wants
permanent birth control, a vasectomy for a man is a much smarter way
to go than for the woman to have a tubal ligation. So, I congratulate
FDA Approves New Treatment for Advanced
Prostate Cancer Patients
Xofigo binds with minerals in the bone to deliver radiation directly to bone tumors, limiting the damage to the surrounding normal tissues. It is the second prostate cancer drug approved by the FDA in the past year that demonstrates an ability to extend the survival of men with metastatic prostate cancer.
Patients who are interested in finding out where and when newly
FDA approved drug Xofigo will be available can call 1-855-696-3446 or
visit the website www.xofigo.com
Source: Pres release
FDA Approves Expanded Use of Prostate Cancer
Zytiga was initially approved in April 2011 for treatment of prostate cancer patients whose disease had progressed after treatment with the chemotherapy drug docetaxel.
The drug decreases production of the male sex hormone testosterone. In prostate cancer, testosterone stimulates prostate tumors to grow. Drugs or surgery are used to reduce testosterone production or to block the hormone's effects.
However, some men have what's called "castration-resistant" or hormone therapy-resistant prostate cancer, which means that prostate cancer cells continue to grow even with low levels of testosterone, the FDA explained in a news release.
The expanded approval is based on a study of 1,088 men with late-stage, hormone therapy-resistant prostate cancer who took either Zytiga (abiraterone acetate) or an inactive placebo in combination with another drug called prednisone.
Median overall survival was just over 35 months for patients who took Zytiga and about 30 months for those who took the placebo, the FDA noted.
The most common side effects among patients taking Zytiga included fatigue, joint discomfort, swelling caused by fluid retention, hot flush, diarrhea, vomiting, cough, high blood pressure, shortness of breath, urinary tract infection and bruising.
This expanded approval of Zytiga was made under the FDA's priority review program, which offers an accelerated six-month review for drugs that may offer major advances in treatment or provide a treatment when no adequate therapy exists.
"Today's approval demonstrates the benefit of further evaluating a drug in an earlier disease setting and provides patients and health care providers the option of using Zytiga earlier in the course of treatment," Dr. Richard Pazdur, director of the Office of Oncology Drug Products in the FDA's Center for Drug Evaluation and Research, said in the FDA news release.
Zytiga is marketed by Pennsylvania-based Janssen Biotech Inc.
New Biopsy Method Could Improve Prostate
These biopsies can be extremely painful and I was put in the hospital several times so they could be done under general anesthesia, said Meier, of Visalia, Calif. It takes about a month to recover.
But researchers are reporting a new method that could put an end to painful prostate biopsies that miss the tumor. Theyve combined magnetic resonance imaging, or MRI, with ultrasound in a way that can guide a skilled doctor right to a prostate tumor.
Dr. Leonard Marks, a professor of urology at the University of California Los Angeles and colleagues report their method in the Journal of Urology. They say it helped them identify prostate tumors in 53 percent of 171 men who volunteered to try it.
The findings could help solve one of the biggest problems of prostate cancer. Theres a blood analysis called a PSA test that can help doctors guess that a man may be developing prostate cancer. Prostate specifc antigen or PSA is made only by prostate cells and they produce a lot more of it when they are cancerous.
But the prostate also naturally enlarges as men get older, which can send PSA levels up. And inflammation caused by an infection or even something as simple as a bicycle ride, can also send levels up.
Because the walnut-sized prostate gland is so hard to reach, doctors have to do a so-called blind biopsy. They take a few chunks of tissue and hope they get a piece of any tumor so they can decide how aggressive the cancer is. But they can completely miss the tumor and get healthy tissue.
Thats what happened to Meier. His PSA started rising in 2008, but repeated biopsies showed no sign of cancer.
The doctor I was going to did three rounds of biopsies and he never could find it, Meier said in a telephone interview.
Some men might be comfortable with so-called watchful waiting. But others are anxious when they think they may have cancer but dont really know and Meier was one of them. He went to a doctor in Santa Barbara for a second opinion, and got yet another biopsy. It was negative.
Every time they did a biopsy they couldnt find anything, Meier said.
So the second doctor started treating Meier for an enlarged prostate. But the PSA kept going up. I new in my mind something was wrong, Meier said.
By 2011 his PSA was nearly 18 a huge rise from a normal reading of 4. Meier was referred to UCLA. He had an MRI in Markss lab, and it showed a tumor.
Using standard technology, a urologist would still have to guess where the tumor was to get a sample so a pathologist could determine if it was likely to spread. The new technology that Marks helped develop combines the MRI image of a suspected tumor with ultrasound, so the urologist can guide the biopsy needle right there.
Marks got a piece of Meiers tumor, and it was an aggressive type.
It had gone out of the prostate gland a little bit and gone into whats called the seminal vesicles, Meier said.
Meier had his prostate surgically removed, as well as two dozen surroudning lymph glands. As of now it looks pretty good, he said.
The 171 men in the UCLA study were all being watched for possible prostate cancer, or were under observation for slow-growing tumors. While most prostate tumors grow slowly, some become aggressive and spread quickly, and it's often hard to tell what type a man has.
Men with early state prostate cancer can choose from a range of treatments, including surgery, guided radiation and a treatment using radioactive seeds that kill prostate tissue.
Prostate cancer is the biggest cancer killer of U.S. men, after lung cancer. Its diagnosed in more than 240,000 men a year and kills more than 28,000, according to the American Cancer Society.
Most men with prostate cancer will never develop symptoms, and a biopsy is the only way to take a look at the tumor cells and decide how dangerous the cancer is. Because of the uncertainty, last May the U.S. Preventive Services Task Force recommended that routine PSA screening be stopped. It said too many men were getting painful biopsies and even surgery and radiation that were not necessary.
Several studies have shown early screening hasnt lowered the prostate cancer death rate, and one study projected that a million men had been treated needlessly for the disease between 1986 and 2000.
Because of an elevated PSA level, some men may be diagnosed with a prostate cancer that they would have never even known about at all. It would never have lead to their death, or even caused any symptoms, the American Cancer Society says.Treatments like surgery and radiation can have urinary, bowel, and/or sexual side effects that may seriously affect a man's quality of life.
Targeting biopsies wont solve the problems caused by PSA screenings, but they can help doctors and patients decide sooner whether a man really does need treatment for his cancer.
Marks and colleagues said if a tumor looked dangerous on an MRI, the biopsy usually confirmed that it was.
Biopsy findings correlate with the level of suspicion on
MRI. Targeted prostate biopsy has the potential to improve the
diagnosis of prostate cancer and may aid in the selection of patients
for active surveillance and focal therapy, Markss team
may cause diabetes
Men with advanced
prostate cancer earn $100 for taking online survey
The goal of the survey is to understand the range of issues, concerns, and perceptions among men with advanced prostate cancer. If you've 1) been on your current hormonal therapy for five years or more or 2) your physician switched you to a different hormonal therapy because your PSA started to rise while you were taking a previous hormonal therapy, we need your help in completing this survey.
The survey is strictly for market research purposes and your individual answers will be kept completely confidential. There will be no sales follow-up and your personal information will not be shared with anyone.
Participant quotas are limited, so see if you qualify for this
online survey right now clicking on www.surveysbw.com/healthsurvey3
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Inhibitors of Novel Cancer Target
Attack Tumor on Two Fronts-AACR Proceedings Highlight Research of
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HRT Patches for Men: They help
in prostate cancer fight
External Beam Radiotherapy can Relieve
Metastatic Bone Pain
Approvimately 90% of adults can be treated or cured of incontinence but haven't sought professional help.
Information is designed for educational purposes. We are not engaged in rendering medical or psychological advice or professional services. Any decisions should be made in conjunction with your physician or therapist. We will not be liable for any complications, injuries or other medical accidents arising from or in connection with, the use of or reliance upon, any information on our web site.